Which immune reactions are seen in patients with crusted scabies, and which are seen in classic scabies?

Updated: Oct 13, 2020
  • Author: Megan Barry, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Serum immunoglobulin E (IgE) and IgG levels are extremely high in patients with crusted scabies, yet the immune reaction does not seem to be protective. Cell-mediated immunity in classic scabies demonstrates T4-cell predominance in the dermal infiltrate, while one study suggests a T8-cell predominance in crusted scabies.


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