What is the pathophysiology of seborrheic dermatitis?

Updated: Nov 13, 2020
  • Author: Marc Zachary Handler, MD; Chief Editor: William D James, MD  more...
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Answer

The exact pathophysiology remains unclear. Malassezia organisms are probably not the cause but are a cofactor linked to a T-cell depression, increased sebum levels, and an activation of the alternative complement pathway. Persons prone to this dermatitis also may have a skin-barrier dysfunction. [25, 26]


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