What is the role of serology in the evaluation of guttate psoriasis?

Updated: Oct 16, 2020
  • Author: Kirstin Altman, MD; Chief Editor: Dirk M Elston, MD  more...
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Levels of antibodies to streptolysin O, hyaluronidase, and deoxyribonuclease B may be elevated in more than half the patients with guttate psoriasis. Significant elevations of antistreptococcal M6 protein have been documented. Routine screening in asymptomatic patients is controversial. Patients with symptoms suggestive of a streptococcal infection should undergo appropriate laboratory testing.

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