What are implications of immunologic changes in the etiology of guttate psoriasis?

Updated: Oct 03, 2019
  • Author: Kirstin Altman, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Answer

Epidermal Langerhans cell migration is inhibited in early-onset, plaque-type psoriasis. Altered Langerhans cell migration has recently also been demonstrated in patients with guttate psoriasis. A small study revealed decreased migration compared with healthy controls. In patients with resolved guttate psoriasis, the epidermal Langerhans cell migration was normal. [13]


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