What are the options for topical therapy in the treatment of onychomycosis?

Updated: Oct 05, 2020
  • Author: Antonella Tosti, MD; Chief Editor: Dirk M Elston, MD  more...
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Topical therapy for onychomycosis is as follows:

  • Ciclopirox olamine 8% nail lacquer solution

  • Amorolfine or bifonazole/urea (available outside the United States)

  • Efinaconazole 10% topical solution (the first FDA-approved topical triazole for toenail onychomycosis)

  • Tavaborole 0.5% topical solution, an oxaborole solution (boron-containing compound)

  • Can be used in WSO and DLSO limited to the distal nail

  • Should be limited to cases involving less than half of the distal nail plate or for patients unable to tolerate systemic treatment

  • Topical treatments may be useful to prevent recurrence in patients cured with systemic agents

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