Which clinical history findings are characteristic of nodular localized cutaneous amyloidosis (NLCA)?

Updated: Nov 15, 2016
  • Author: Nicholas V Nguyen, MD; Chief Editor: Dirk M Elston, MD  more...
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Patient history may include the following:

  • Nodular localized cutaneous amyloidosis lesions usually are asymptomatic.

  • Patients can present with single or multiple lesions.

  • In some reports, lesions were present for several years before patients sought medical attention.

  • Troublesome aspects of nodular localized cutaneous amyloidosis primarily result from patient concerns about appearance, although plaques eventually fissured in one patient in whom the plantar aspects of the feet were affected.

  • Up to 25% of reported cases of NLCA have been in patients with Sjögren syndrome. [14]

  • In some cases, patients have given a history of preceding trauma. [3, 15]

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