What is acral acanthosis nigricans (AN)?

Updated: Oct 14, 2020
  • Author: Jason H Miller, MD; Chief Editor: William D James, MD  more...
  • Print
Answer

Acral acanthosis nigricans (acral acanthotic anomaly) occurs in patients who are in otherwise good health. Acral acanthosis nigricans is most common in dark-skinned individuals, especially those of African American or sub-Saharan African descent. The hyperkeratotic velvety lesions are most prominent over the dorsal aspects of the hands and feet, with knuckle hyperpigmentation often most prominent.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!