How is liposarcoma staged?

Updated: Mar 18, 2020
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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The Enneking oncologic staging system defines the biologic behavior of primary tumors. This system has proven to be effective in planning surgery for limb lesions (eg, intralesional, marginal, wide, radical) and in evaluating its results. Note the following:

  • The Enneking staging system divides benign tumors into 3 stages: S1, S2, and S3.

  • Localized malignant tumors are divided into 4 stages: IA, IB, IIA, and IIB.

  • Two other stages include metastatic high-grade intracompartmental tumors, or stage IIIA tumors, and extracompartmental malignant tumors, or stage IIIB tumors.

  • This classification scheme was formerly used to describe long-bone tumors.

  • This staging system is based on a complete preoperative workup that includes an assessment of the clinical features; the radiographic pattern and CT and MRI data regarding the extension of the tumor; the peculiar imaging features of the tumor and its relationship to the neighboring tissues; the findings from isotopic scanning, which provides information about local aggression and systemic diffusion; and the histologic findings obtained at biopsy.

Surgical staging is appropriate only after the diagnosis is established and the oncologic stage is determined.

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