How is recurrent/metastatic cutaneous melanoma diagnosed?

Updated: Oct 13, 2020
  • Author: Susan M Swetter, MD; Chief Editor: Dirk M Elston, MD  more...
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The diagnosis of recurrent/metastatic disease and new primary melanoma depends on a routine evaluation schedule that varies according to the following:

  • Tumor depth

  • The presence of histologic ulceration

  • Mitotic rate in the primary tumor

  • Regional lymph node status

  • Results of the examination of the melanoma scar

  • Results of the examination of regional and distant lymph node basins

  • The presence of hepatosplenomegaly upon abdominal examination

  • Mole pattern and examination findings from the entire cutaneous surface for new primaries

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