Which medications in the drug class Corticosteroids are used in the treatment of Langerhans Cell Histiocytosis?

Updated: Jun 12, 2020
  • Author: Christopher R Shea, MD; Chief Editor: William D James, MD  more...
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Answer

Corticosteroids

These agents have anti-inflammatory properties and cause profound and varied metabolic effects. Corticosteroids modify the body's immune response to diverse stimuli.

Prednisone (Deltasone, Liquid Pred, Meticorten, Orasone, Prednicen-M, Sterapred)

Prednisone is also known as deltacortisone and deltadehydrocortisone. It may decrease inflammation by reversing increased capillary permeability and suppressing PMN activity.

Use the lowest effective dose in elderly patients. Pediatric dosing depends on the condition being treated and the response of the patient; the dose for infants and children should be based on severity and the response of the patient rather than on strict adherence to the dose indicated by age, weight, or body surface area.

Prednisolone (AK-Pred, Articulose-50, Delta-Cortef, Econopred, Inflamase)

Prednisolone is also known as delta hydrocortisone, metacortandralone, prednisolone acetate, and prednisolone sodium phosphate. It decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reducing capillary permeability.

Methylprednisolone (Adlone, A-methaPred, depMedalone, Depoject, Depopred)

Methylprednisolone is also known as 6-alpha-methylprednisolone, methylprednisolone acetate, and methylprednisolone sodium succinate. By reversing increased capillary permeability and suppressing PMN activity, it may decrease inflammation.


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