Which medications in the drug class Antimetabolites are used in the treatment of Pityriasis Lichenoides?

Updated: Sep 11, 2020
  • Author: Jeffrey P Callen, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Antimetabolites

Methotrexate inhibits dihydrofolate reductase, thereby hindering DNA synthesis and cell reproduction.

Methotrexate (Folex, Rheumatrex)

Methotrexate may suppress the immune system. It ameliorates symptoms of inflammation (eg, pain, swelling, stiffness). A satisfactory response is seen in 3-6 weeks following administration. Adjust the dose gradually to attain a satisfactory response.


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