What is the role of infection in the etiology of pityriasis lichenoides?

Updated: Sep 11, 2020
  • Author: Jeffrey P Callen, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

In addition to EBV, Toxoplasma gondii, and HIV, a number of other infectious agents have been implicated. The following observations are provocative but may be chance associations. Note the following:

  • Case reports have suggested that parvovirus B19 and adenovirus can trigger Mucha-Habermann disease.

  • Herpes simplex has been associated with onset of the disease.

  • One case report also describes resolution of PLC after tonsillectomy, with throat cultures yielding Staphylococcus aureus and group A beta hemolytic streptococci.

  • Piamphongsant similarly found coagulase-positive staphylococci on throat cultures in 4 of 10 patients, with some improvement of cutaneous lesions using oral tetracycline. [15]

  • Freeze-dried live attenuated measles vaccine administered by injection has been associated with Mucha-Habermann disease [16] .

  • A 12-year-old boy presented with PLEVA five days following influenza vaccination. [17]


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