Which medications in the drug class Hepatic enzyme inducing agents are used in the treatment of Pruritus and Systemic Disease?

Updated: Mar 03, 2020
  • Author: David F Butler, MD; Chief Editor: William D James, MD  more...
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Answer

Hepatic enzyme inducing agents

These agents are used to treat cholestatic pruritus.

Rifampin (Rifadin)

Rifampin is traditionally used as an antibiotic with the known mechanism of action of inhibiting RNA synthesis in bacteria. It also inhibits the reuptake of hepatic bile acid and induces hepatic mixed-function oxidases, which may detoxify hepatic bile acids. Consider this drug when a course of cholestyramine fails.


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