What is the role of calcimimetics in the treatment of calciphylaxis?

Updated: Feb 24, 2020
  • Author: Julia R Nunley, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Calcimimetics such as cinacalcet hydrochloride may be beneficial in cases of hyperparathyroidism. [50, 51, 52] These agents increase the sensitivity of the calcium receptors to available calcium, thereby decreasing PTH secretion. Studies have shown efficacy in decreasing PTH, calcium, and phosphate levels. Reports of successful treatment with these agents as adjunctive therapy for calciphylaxis are emerging. [53, 54]


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