Which cutaneous malignancies have been reported following renal transplantation?

Updated: Mar 05, 2020
  • Author: Julia R Nunley, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Other malignancies

Although Kaposi sarcoma is the most commonly reported sarcoma in renal transplant recipient, other cutaneous sarcomas have been reported. Malignant fibrous histiocytomas, atypical fibroxanthomas, and dermatofibrosarcoma protuberans have been reported in renal transplant recipients, although the incidence of these malignancies is unknown. Several cases of Merkel cell carcinoma (MCC) occurring in renal transplant recipients have been reported. [55] Most lesions develop on the head and neck or the extremities. This is an aggressive tumor with a high propensity to recur or metastasize. Overall mortality associated with Merkel cell carcinoma is 35%. Interestingly, reports exist of SCC and MCC occurring simultaneously.

Although lymphomas are the second most common malignancy in transplant recipients, cutaneous lymphomas are relatively rare. Whereas cutaneous T-cell lymphomas have been described, cutaneous B-cell lymphomas are more common in the transplant population. [56]


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