Which medications in the drug class Opioid Analgesics are used in the treatment of Reduction of Shoulder Dislocation?

Updated: Aug 17, 2018
  • Author: Anantha K Mallia, DO, FACEP; Chief Editor: Erik D Schraga, MD  more...
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Answer

Opioid Analgesics

Analgesics ensure patient comfort, promote pulmonary toilet, and have sedating properties that are beneficial for patients who experience pain.

Fentanyl citrate (Duragesic, Abstral, Actiq, Fentora, Onsolis)

Fentanyl citrate is a synthetic opioid that has 75-200 times more potency and a much shorter half-life than morphine sulfate. It has fewer hypotensive effects than morphine and is safer in patients with hyperactive airway disease because of minimal or no associated histamine release. By itself, fentanyl citrate causes little cardiovascular compromise, although the addition of benzodiazepines or other sedatives may result in decreased cardiac output and blood pressure.

Fentanyl citrate is highly lipophilic and protein-bound. Prolonged exposure to it leads to accumulation of the drug in fat and delays the weaning process. Consider continuous infusion because of the medication's short half-life.

Remifentanil (Ultiva)

Remifentanil binds mu-opioid receptors at various sites within the CNS.

Morphine sulfate (Duramorph, Astramorph, MS Contin, Avinza, Kadian)

Morphine sulfate is the drug of choice for analgesia, owing to its reliable and predictable effects, safety profile, and ease of reversibility with naloxone.

Various intravenous doses are used; it is commonly titrated until the desired effect is obtained.


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