What are the treatment options for candidiasis in HIV?

Updated: Jan 17, 2020
  • Author: Richard Harold "Hal" Flowers, IV, MD; Chief Editor: Dirk M Elston, MD  more...
  • Print
Answer

Topical therapy with agents such as nystatin and clotrimazole are the mainstay of treatment. Treatment with topical therapies may be effective in the early stages of HIV infection. Oral treatment with a 2-week course of antifungal therapy (itraconazole, fluconazole, ketoconazole) is indicated in more refractory cases. In patients who are significantly immunocompromised, maintenance therapy on an intermittent (alternate days to twice weekly dosing of ketoconazole 200 mg or fluconazole 100 mg) or continuous basis may be required to provide symptomatic relief. In general, the goal is the cessation of therapy once clinical symptoms have subsided, since prolonged therapy may promote the development of drug-resistant organisms.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!