Which histologic findings are characteristic of cutaneous candidiasis?

Updated: Jan 17, 2020
  • Author: Richard Harold "Hal" Flowers, IV, MD; Chief Editor: Dirk M Elston, MD  more...
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A skin biopsy specimen stained with a periodic acid-Schiff stain reveals nonseptated hyphae. The presence of nonseptated hyphae allows cutaneous candidiasis to be distinguished from tinea. Classically, neutrophils are seen in the stratum corneum. [57] In the subsequent epidermis, focal spongiosis and mild acanthosis may be noted. [57]

Of all the types of Candida, the electron microscope shows that C albicans is the most confluent in its adherence to the skin. [58]

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