How is simple intertrigo treated?

Updated: Nov 13, 2020
  • Author: Paras Vakharia, PharmD; Chief Editor: William D James, MD  more...
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Simple intertrigo may be treated with drying agents (eg, talc, cornstarch).

Where appropriate, antimycotic agents (miconazole, clotrimazole) are helpful, especially if used with a mild- to mid-potency (class III-VI) steroid for a short duration. Avoid using stronger topical steroids because the occlusive effect of skin folds can accelerate the development of skin atrophy and striae. Castellani paint (carbol-fuchsin paint) also can be helpful, especially in the toe web spaces.

Formulations combining protective agents, antimicrobials, and topical steroids may be helpful, including the following [17, 18] :

  • Triple Paste contains petrolatum, zinc oxide paste, and aluminum acetate (Burow) solution applied qs ad (ie, in a sufficient quantity).

  • Greer goo is composed of nystatin (Mycostatin) powder 4 million U, hydrocortisone powder 1.2 g, and zinc oxide paste 4 oz applied qs ad (ie, in a sufficient quantity).

A thick coat of these protective barrier creams should be applied. Commercially available barrier pastes sold for diaper dermatitis (eg, Desitin) can be helpful, as can absorbent diapers. Tetrix, a prescription dimethicone barrier cream, may be more protective and less greasy than traditional petrolatum-based barrier products such as zinc oxide ointment.

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