Which medications in the drug class Topical Skin Products are used in the treatment of Lymphedema?

Updated: Mar 24, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: William D James, MD  more...
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Topical Skin Products

Topical emollients and keratolytics may improve secondary epidermal changes.

Ammonium lactate lotion (AmLactin, AmLactin XL, Lac-Hydrin, Gen-Hydrolac)

This agent is believed to act as a humectant when applied to skin. This may influence hydration of the stratum corneum. In addition, when applied to the skin, ammonium lactate lotion may decrease corneocyte cohesion. The mechanism by which this is accomplished is not yet known.

Found in a variety of topical emollient lotions, ammonium lactate is used to decrease scaling and pruritus. Ammonium lactate 5% lotion is available over the counter; lactic acid 12% cream and lotion are available by prescription.

Urea, topical (Carmol, Keralac, Ureacin)

Topical urea promotes hydration and removal of excess keratin in conditions of hyperkeratosis.

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