How is filariasis treated in patients with lymphedema?

Updated: Mar 24, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: William D James, MD  more...
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Filariasis has been treated with diethylcarbamazine and albendazole. [74] The combination of 2-week doxycycline with rifampicin may produce moderate macrofilaricidal activity against Wuchereria bancrofti. [27] Doxycycline itself may improve filarial lymphedema. [75]  The mass administration of ivermectin and albendazole has proven effective for eliminating lymphatic filariasis in endemic areas, [76] however, with continued recognition that additional measures may be needed as it can spillover into Europe and North America. Moxidectin may provide longer microfilarial suppression compared with ivermectin and may prove better for onchocerciasis elimination. [77]

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