How is cellulitis treated in patients with lymphedema?

Updated: Mar 24, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: William D James, MD  more...
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Even with excellent skin care, chronic cellulitis may occur. At the earliest signs of infection, institute topical or systemic antifungal or antimicrobial therapy to prevent the development of sepsis. Sometimes long-term treatment with antifungal and antibacterial treatments can result in a remission of the recurrent cellulitis (75-85%). Long-term, prophylactic treatment with antimicrobial agents such as penicillin, cephalexin, or erythromycin may be required in 15-25% of patients experiencing recurrent lymphangitis or cellulitis. [72, 73]

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