What is the prevalence of inherited thrombophilia?

Updated: Aug 31, 2020
  • Author: Padma Chitnavis, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

In the general population, the prevalence of an inherited thrombotic syndrome is presently estimated to be 1 individual in 2500-5000 population; the prevalence increases to 4% in patients with a past history of thrombosis. [5] A past history of deep venous thrombosis (DVT) increases the likelihood of new postoperative venous thrombosis from 26% to 68%, whereas a past history of both DVT and pulmonary embolism (PE) is predictive of a near 100% rate of thrombosis. [6] Further detail regarding hypercoagulable conditions is beyond the scope of this article. The most common conditions are discussed below. For additional information, the reader is referred to multiple review articles on hypercoagulable conditions. [3, 5, 7, 8]


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