Which medications in the drug class Sclerosing Agents are used in the treatment of Venous Insufficiency?

Updated: Oct 22, 2018
  • Author: Robert Weiss, MD; Chief Editor: William D James, MD  more...
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Answer

Sclerosing Agents

Sclerosing agents are used for the primary sclerosis of reflux pathways and for the ablation of friable thin-walled veins judged to be at high risk for rupture and hemorrhage.

Sodium tetradecyl sulfate (Sotradecol)

Primary sclerotherapy is the treatment of choice for ablation of refluxing superficial venous circuits in the absence of saphenofemoral junctional reflux. It is also the treatment of choice for ablation of venous bleeding sites and friable thin-walled varices. In general, a 1% concentration is most useful; in larger varicosities, a 3% concentration may be used as a liquid. Foam may be made by agitating a 1:4 mixture of solution and air. When a foamed solution is used, a concentration of 0.25-0.5% is sufficient.


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