What is the role of lab studies in the diagnosis of venous insufficiency?

Updated: Oct 22, 2018
  • Author: Robert Weiss, MD; Chief Editor: William D James, MD  more...
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Many patients with venous insufficiency have clinically unrecognized chronic recurrent varicose thrombosis due to stasis in areas with abnormal veins. Such patients may have elevated levels of D-dimer. This finding reduces the usefulness of that test for the evaluation of patients with suspected acute venous thromboembolic disease.

Laboratory tests may be helpful in patients with venous insufficiency due to Klippel-Trénaunay-Weber (KTW) syndrome because such patients can develop consumptive thrombocytopenia.

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