Which medications in the drug class Nonsteroidal anti-inflammatory agents are used in the treatment of Urticarial Vasculitis?

Updated: Jun 07, 2018
  • Author: Darius Mehregan, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Nonsteroidal anti-inflammatory agents

Nonsteroidal anti-inflammatory agents are most commonly used for relief of mild to moderate pain. The basis behind the use of indomethacin is empiric. It was used with some effectiveness on the cutaneous manifestations of the disease in several case reports.

Indomethacin (Indocin)

Indomethacin is the only NSAID reported effective in urticarial vasculitis. It is rapidly absorbed; metabolism occurs in the liver by demethylation, deacetylation, and glucuronide conjugation. Indomethacin inhibits prostaglandin synthesis.


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