Which medications in the drug class Cytotoxic agents are used in the treatment of Urticarial Vasculitis?

Updated: Jun 07, 2018
  • Author: Darius Mehregan, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Cytotoxic agents

Azathioprine may be used as a steroid-sparing agent once other therapeutic options have been exhausted. Measurement of thiopurine methyltransferase can help ensure safe and optimal treatment with azathioprine.

Azathioprine (Imuran)

Azathioprine is a purine precursor that affects the formation of adenine and guanine. This results in impaired DNA synthesis in immunocompetent cells such as lymphocytes, which are dividing rapidly during an inflammatory process. Azathioprine has a slow onset of action; it is rarely used as monotherapy.


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