Which medications in the drug class Glucocorticoids are used in the treatment of Urticarial Vasculitis?

Updated: Jun 07, 2018
  • Author: Darius Mehregan, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Glucocorticoids

Glucocorticoids are often the treatment of choice. However, given their long-term adverse effect profiles, they are used only for significant cutaneous disease or systemic involvement. For long-term treatment, a combination of prednisone and another medication may be required.

Prednisone (Deltasone)

Although prednisone is most effective, adverse effect profiles preclude it from use as a first-line agent. Consider it only after failure of antihistamines, indomethacin, colchicine, dapsone, or hydroxychloroquine. Its effect on urticarial vasculitis likely is mediated by its anti-inflammatory effect. This class of medications decreases capillary permeability and inhibits the mitotic rate of lymphocytes.


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