How are pigmented purpuric dermatoses treated?

Updated: Jun 07, 2018
  • Author: Darius Mehregan, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

No medical intervention is of proven benefit for the treatment of the pigmented purpuric dermatoses.

Pruritus may be alleviated by the use of topical corticosteroids and antihistamines.

Associated venous stasis should be treated by compression hosiery.

Prolonged leg dependency should be avoided.

The use of narrowband UVB and psoralen plus UVA have shown to be effective treatments for some patients with pigmented purpuric dermatoses. [21, 22, 23, 24, 25]

Tamaki et al reported successful treatment of pigmented purpuric dermatoses using griseofulvin. [26] Treatment with oral cyclosporin has also been successful. [27]

Successful therapy with ascorbic acid (500 mg twice daily) and rutoside (50 mg twice daily) has also been reported. [28] Anecdotal data exist for calcineurin-inhibitors, colchicine, pentoxifylline, immunosuppressants, ultraviolet therapy, and laser therapy. [29]


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