Which medications in the drug class Beta-adrenergic Blocker are used in the treatment of Infantile Hemangioma?

Updated: Nov 09, 2020
  • Author: Richard J Antaya, MD; Chief Editor: William D James, MD  more...
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Beta-adrenergic Blocker

Selective beta-blockers specifically block beta-1 receptors alone, although they can be nonselective at higher doses.

Caution should be used in administering these agents in the setting of asthma or severe chronic obstructive pulmonary disease (COPD), regardless of beta-selectivity profile. In addition, exacerbations of angina and, in some cases, myocardial infarction have been reported following abrupt discontinuance of beta-blocker therapy. The doses should be gradually reduced over at least a few weeks.

Propranolol (Hemangeol)

The mechanism of propranolol's effects on infantile hemangiomas is not well understood. Propranolol is a nonselective beta-adrenergic receptor blocking agent possessing no other autonomic nervous system activity. It is indicated for treatment of proliferating hemangioma requiring systemic therapy. It is available as an oral solution (4.28 mg/mL).

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