Which medications are used in the treatment of infantile hemangioma?

Updated: Feb 06, 2019
  • Author: Richard J Antaya, MD; Chief Editor: William D James, MD  more...
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Answer

The majority of infantile hemangiomas do not require any medical or surgical intervention. [8] Historically, medical care of clinically significant hemangiomas had been limited to a few medications, including glucocorticosteroids (topical, intralesional, and oral), interferon alfa, and, rarely, vincristine and topical imiquimod. [63] Beta-blockers, most specifically propranolol, [64] have been shown to induce involution of infantile hemangiomas and are now considered first-line treatment for problematic infantile hemangiomas. [65, 66, 67, 68] There is an FDA-approved formulation of propranolol solution indicated for the treatment of infantile hemangiomas for infants aged 5 weeks to 5 months. [69]


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