Which patient groups have the highest prevalence of HIV-associated lipodystrophy?

Updated: Sep 05, 2019
  • Author: David T Robles, MD, PhD, FAAD; Chief Editor: Dirk M Elston, MD  more...
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The risk of lipoatrophy is higher in whites (5.4 odds ratio) than in blacks. Women are at a higher risk of lipodystrophy than men (1.9 relative risk). Women are more likely to report fat accumulation in the abdomen and breasts and hypertriglyceridemia, whereas men are more likely to describe fat depletion from the face and extremities, along with hypertension and hypercholesterolemia. [43] Increasing age is a risk factor in the development of this syndrome.

Over the last 12 years, the prevalence of lipodystrophy in HIV-infected men has decreased, yet the prevalence of metabolic syndrome and cardiovascular disease risk has increased. [44]

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