Which medications in the drug class Immunosuppressants are used in the treatment of Oral Lichen Planus?

Updated: Mar 29, 2018
  • Author: Jaisri R Thoppay, DDS, MBA, MS; Chief Editor: Jeff Burgess, DDS, MSD  more...
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Answer

Immunosuppressants

These agents are used for painful, erythematous, or erosive oral lichen planus that is recalcitrant to topical corticosteroids.

Azathioprine (Imuran, Azasan)

Azathioprine antagonizes purine metabolism. It inhibits the synthesis of DNA, RNA, and proteins. Azathioprine may decrease the proliferation of immune cells, resulting in lower autoimmune activity.


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