What are potential triggers for oral lichen planus (OLP)?

Updated: Sep 15, 2020
  • Author: Jaisri R Thoppay, DDS, MBA, MS; Chief Editor: Jeff Burgess, DDS, MSD  more...
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Oral mucosal lichenoid lesions may occur after potential triggers. Such triggers are often the administration of systemic drugs such as nonsteroidal anti-inflammatory drugs (NSAIDs), sulfonylureas, antimalarials, beta-blockers, and some angiotensin-converting enzyme (ACE) inhibitors. The period between the commencement of the drug therapy and the clinical appearance of oral lichen planus–like disease varies. Products such as cinnamon, mints, tooth-whitening products, or red wine can trigger oral lichenoid reactions. [34]

Occasionally, dental restoration may cause an oral lichenoid reaction often seen on soft tissues in opposition or proximal to the dental restoration. Such presentations may be localized to that area, unlike diffuse presentations of oral lichen planus. Patients with an associated allergy to metals or components of the appliance should be evaluated by means of patch testing. [39]

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