Which antimicrobials are used in the treatment of cheilitis granulomatosa?

Updated: Jun 21, 2018
  • Author: Alan Snyder; Chief Editor: William D James, MD  more...
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Answer

Antimicrobials are as follows:

  • Tetracycline (used for anti-inflammatory activity)
  • Azithromycin [51]
  • Metronidazole [38, 39]
  • Minocycline [52]
  • Roxithromycin [53]
  • Antibiotic treatment of dental abscess - Resulted in remission in anecdotal cases

Intralesional corticosteroid (triamcinolone) injections may reduce swelling. Systemic corticosteroids are rarely indicated and not all patients respond. Clofazimine, dapsone, tacrolimus, thalidomide, or antitumor necrosis factor biologics may be needed. [33] No large randomized, controlled trials have been recorded with potential therapies such as tacrolimus, thalidomide, or infliximab.


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