How is angular stomatitis (perlèche, angular cheilitis) characterized?

Updated: Mar 27, 2020
  • Author: Surbhi Gupta; Chief Editor: William D James, MD  more...
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This is a subset of erythematous candidiasis. Lesions affect the angles of the mouth, causing soreness, erythema, and fissuring. Both yeasts (candidal) and bacteria (especially Staphylococcus aureus) may be involved. 

Angular cheilitis; a common form of oral candidias Angular cheilitis; a common form of oral candidiasis, typically seen in patients with denture-related stomatitis, especially those in whom the denture needs adjustment. In others, it may be a sign of diabetes, nutritional deficiency, or immune defect.

Angular cheilitis is not specific for mucosal candidiasis. It can also be seen with vitamin B-12 or iron deficiency, Down syndrome, orofacial granulomatosis, Crohn disease, HIV infection, or diabetes.

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