What is the role of exfoliants in the treatment of hidradenitis suppurativa (HS)?

Updated: Nov 20, 2020
  • Author: Marina Jovanovic, MD, PhD; Chief Editor: William D James, MD  more...
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Exfoliants and peels with topical 15% resorcinol cream, which is the only exfoliant formulated as an oil/water cream with emulsifying waxes, exhibits keratolytic, antipruritic, and antiseptic activities. Resorcinol is indicated in recurrent lesions in patients with Hurley stage I or II hidradenitis suppurativa. In a 2010 study, topical treatment with 15% resorcinol reduced pain from painful nodules in all patients with hidradenitis suppurativa. However, more trials are needed to confirm its efficacy. [122]  No formal studies or guidelines are available on the use of resorcinol in pregnancy.

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