Which combination therapies are recommended for the treatment of hidradenitis suppurativa (HS)?

Updated: Nov 20, 2020
  • Author: Marina Jovanovic, MD, PhD; Chief Editor: William D James, MD  more...
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Clindamycin at 300 mg twice daily in combination with rifampin at 300 mg twice daily has been recommended in a 2012 clinical practice article by Jemec, especially in light of the emerging presence of methicillin-resistant Staphylococcus aureus (MRSA). [104]

Systemic treatment with a combination of rifampin-moxifloxacin-metronidazole, either alone or preceded by systemic ceftriaxone treatment, is recommended for resistant stage II and III disease. After 12 weeks of initial treatment, the therapy should be continued for an additional 12 weeks using a combination of moxifloxacin and rifampin. [1]

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