What is the initial dosing regimen for the treatment of mild hidradenitis suppurativa (HS)?

Updated: Nov 20, 2020
  • Author: Marina Jovanovic, MD, PhD; Chief Editor: William D James, MD  more...
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The proposed dosing regimen as a first-line treatment option in patients with mild hidradenitis suppurativa PGA or localized Hurley I/mild Hurley II stage, especially when there are no deep inflammatory lesions (abscesses), is topical clindamycin 1% solution/gel twice daily for 12 weeks and/or tetracycline 500 mg orally twice daily for 4 months.

If patient fails to exhibit a response to treatment or for a PGA of moderate-to-severe disease with moderate and severe hidradenitis suppurativa PGA or Hurley II stage, considered clindamycin 300 mg orally twice daily with rifampin 600 orally twice daily for 10 weeks.

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