What are the histologic findings of hidradenitis suppurativa (HS)?

Updated: Nov 20, 2020
  • Author: Marina Jovanovic, MD, PhD; Chief Editor: William D James, MD  more...
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Histologically, the fundamental change in hidradenitis suppurativa is the same as in acne vulgaris, namely, hyperkeratosis of the infundibulum that results in comedolike horny impactions. [73] Some evidence suggests that the occlusion of abnormal hair follicles may play an important part in the initiation of the lesions. [25, 83] Follicular occlusion was found in all specimens compared with controls and regardless of disease duration. [38] Folliculitis and perifollicular inflammation are common and occur in about two thirds of cases, with or without follicular occlusion.

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