What inflammatory changes occur in the initial stages of hidradenitis suppurativa (HS)?

Updated: Nov 20, 2020
  • Author: Marina Jovanovic, MD, PhD; Chief Editor: William D James, MD  more...
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The earliest change is plugging, which occurs in follicular hyperkeratosis with infundibulofolliculitis. This obstructs the apocrine gland ducts and perifolliculitis around the ducts. Whether this initial inflammatory change is due to a bacterial infection or factors similar to those involved in acne formation is not known.

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