What is the role of brimonidine in the treatment of rosacea?

Updated: Aug 14, 2018
  • Author: Agnieszka Kupiec Banasikowska, MD; Chief Editor: William D James, MD  more...
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Answer

A topical form of the alpha-2 agonist brimonidine was approved by the FDA in August 2013 for treatment of erythema associated with rosacea. Approval was based on data collected from more than 550 patients enrolled in two phase 3 clinical studies of one-month duration. The results from both studies showed that adults who used brimonidine topical gel demonstrated significantly greater improvement in the facial redness of rosacea than those who used vehicle gel alone. [22] In addition, a long-term study in 276 subjects who used brimonidine topical gel for up to 12-months was also conducted.


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