What is zero-therapy and how is it used in the treatment of perioral dermatitis (POD)?

Updated: Aug 16, 2019
  • Author: Hans J Kammler, MD, PhD; Chief Editor: William D James, MD  more...
  • Print
Answer

Zero-therapy is based on the idea that by ceasing use of all topical medications and cosmetics, the underlying causative factor for perioral dermatitis is eliminated. This form of therapy is appropriate in very compliant patients. It may be effective predominantly in cases associated with steroid abuse or when intolerance to cosmetics is suspected. [27, 28]

In every case, an initial worsening of the symptoms may occur with treatment, especially if topical steroids are withdrawn. The patient should be made aware of this complication. In cases of preceding long-term use of topical steroids, steroid weaning with low-dose 0.1-0.5% hydrocortisone cream can be tried initially.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!