What is the role of photodynamic therapy (PDT) in the treatment of keratosis pilaris (KP)?

Updated: Aug 12, 2019
  • Author: Ally N Alai, MD, FAAD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Photodynamic therapy (PDT) using a 2-step combination of a topical photosensitizer and a light source may be used in off-label fashion for the temporary treatment of keratosis pilaris. Available photosensitizers include aminolevulinic acid (Levulan) or methyl levulinate (Metvixia). Light sources include sunlight, blue light (417 nm), red light (630 nm), and multiple laser devices. PDT has been anecdotally reported as effective, but this successful use of off-label photodynamic therapy requires confirmation.


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