What is the role of oxidative stress in the pathophysiology of androgenetic alopecia?

Updated: Feb 12, 2018
  • Author: Robert P Feinstein, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

A study by Kaya Erdogan et al suggested that younger patients with early onset androgenetic alopecia have greater oxidative stress than do individuals without the disease. The study, on males aged 18 to 30 years, found higher total oxidant levels and oxidative stress index values in patients, all of whom had early onset androgenetic alopecia, than in healthy controls. The investigators also reported that within the patient group, the total antioxidant level was negatively correlated with patient age and disease duration. [6]


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