Which biological agents are used to treat alopecia areata?

Updated: Jun 07, 2018
  • Author: Chantal Bolduc, MD, FRCPC; Chief Editor: Dirk M Elston, MD  more...
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Answer

Data are mixed, with many prospective, randomized placebo controlled studies [46, 47] and case reports published in the last few years regarding the use of biologic agents (including adalimumab, alefacept, etanercept and infliximab) in the treatment of alopecia areata, failing to show efficacy, and some patients developed alopecia areata while under treatment with biologic agents for other conditions.

JAK inhibitors now have a significant body of data supporting their efficacy. [48, 49, 50, 51, 52, 53, 54, 55, 56]

Oral alitretinoin shows some promise. [57]


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