What is the efficacy of intralesional steroids for hair regrowth in alopecia areata?

Updated: Jun 07, 2018
  • Author: Chantal Bolduc, MD, FRCPC; Chief Editor: Dirk M Elston, MD  more...
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Answer

In a study including 84 patients, regrowth on treated areas was present in 92% of patients with patchy alopecia areata and 61% of patients with alopecia totalis. Regrowth persisted 3 months after treatment in 71% of patients with patchy alopecia areata and 28% of patients with alopecia totalis. Regrowth usually is seen within 4-6 weeks in responsive patients. Patients with rapidly progressive, extensive, or long-standing alopecia areata tend to respond poorly.

Another study showed regrowth in most patients (480) treated with intralesional steroids, except in two patients with alopecia universalis.

Hair growth may persist for 6-9 months after a single injection. Injections are administered intradermally using a 3-mL syringe and a 30-gauge needle.


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