What are some less commonly used agents for treatment of alopecia areata?

Updated: Aug 06, 2020
  • Author: Chantal Bolduc, MD, FRCPC; Chief Editor: Dirk M Elston, MD  more...
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Answer

Other agents

  • Topical cyclosporine has shown limited efficacy

  • Topical tacrolimus

  • Methotrexate, with or without systemic corticosteroids, has shown mixed results, but continued use is needed to maintain efficacy [4, 5]

  • Systemic cyclosporine, like systemic corticosteroids, offer initial regrowth, but therapy must be continued to maintain efficacy, with a significant risk of adverse events

  • A randomized, double-blind study showed that both positive and negative results have been published with dupilumab; there have also been reports of cases of alopecia areata occurring during treatment with dupilumab


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