What is the esophageal involvement in CREST syndrome?

Updated: Oct 05, 2020
  • Author: Jeanie C Yoon, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

While the entire intestine can be involved in scleroderma, esophageal involvement is most common and most often clinically relevant.

According to Akesson and Wollheim from 1989, [44] dysmotility is common. Cine-esophagram and radionuclide transit time studies demonstrate hypomotility in as many as 75-86% of patients with CREST syndrome. All patients have normal motility of the proximal esophagus, which primarily is striated muscle.


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