Which medications in the drug class Anti-CD20 Monoclonal Antibodies are used in the treatment of Pemphigus Vulgaris?

Updated: Jun 14, 2018
  • Author: Bassam Zeina, MD, PhD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Anti-CD20 Monoclonal Antibodies

Monoclonal antibodies target the CD20 antigen expressed on the surface of pre-B and mature B-lymphocytes. B cells may be acting at multiple sites in the autoimmune/inflammatory process, including T-cell activation and/or proinflammatory cytokine production.

Rituximab (Rituxan)

Rituximab is an anti-CD20 monoclonal antibody indicated for adults with pemphigus vulgaris in combination with short-term corticosteroid therapy.


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